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12/13/2024

Naturopathic Care for Grave’s Disease: Effective Natural Strategies for Autoimmune Hyperthyroidism

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Grave’s disease is an autoimmune condition that causes an overactive thyroid gland, eventually causing damage to your heart, eyes, liver, bone, skin, and skeletal muscles.1 Since it primarily affects the thyroid – a special organ responsible for your metabolism, growth, and development – promptly diagnosing and managing the condition are very important in regulating the processes that keep you alive and healthy, as well as preventing complications associated with high levels of thyroid hormones in the body.
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​​Understanding Autoimmune Hyperthyroidism

Generally, the metabolic processes in your body are fueled by your thyroid hormones, as these primarily control how your cells convert nutrients into energy. Since minimal imbalances can greatly affect the regulatory processes that keep you alive and healthy, your mind and body work together to maintain healthy levels of your thyroid hormones! This collaboration is also known as the hypothalamic-pituitary-thyroid axis. Your hypothalamus first releases thyrotropin-releasing hormone (TRH) which stimulates the cells in your anterior pituitary gland to release thyroid-stimulating hormone (TSH).2  This binds with receptors on your thyroid follicular cells, stimulating the production of thyroid hormones. Your thyroid hormones are then released into the blood to support every organ in the body. ​

Autoimmune hyperthyroidism, or Grave’s disease, occurs due to the presence of autoantibodies, specifically thyroid stimulating immunoglobulin (TSI), which are proteins produced by your immune system that attack your own healthy tissues instead of protecting it from harm. These activate your thyroid-stimulating hormones, thereby stimulating the production of your thyroid hormones and increasing the growth of your thyroid gland.1  High levels of thyroid hormones in the blood can disrupt your cell’s abilities to use and consume energy, causing an imbalance that affects any organ system in the body. 

Signs and Symptoms

The signs and symptoms of hyperthyroidism may vary depending on the age of the patient and severity of the disease upon diagnosis.1 However, patients with Grave’s disease commonly complain of:
  • Intolerance to heat or warm environments
  • Sweating
  • Unintentional weight loss
  • Fatigue
  • Tremors
  • Palpitations (rapid or pronounced heartbeat)
  • Increased frequency of bowel movements
  • Palpable lump in the neck (goiter)
  • Warm and moist skin
  • Hair loss
  • Neck fullness
  • Bulging eyes (exophthalmos)
  • Vision changes
  • Anxiety
  • Insomnia
​

Allopathic Options

Conventional treatment methods for autoimmune hyperthyroidism focus on minimizing the synthesis of your thyroid hormones either by lifetime antithyroid medications, treatment with radioactive iodine to permanently damage the thyroid gland and prevent its activity, or removal of the thyroid gland via surgery (thyroidectomy).1 Although beneficial, these medications may put you at risk of adverse effects, including allergic reactions and liver damage. Radioactive iodine, on the other hand, involves heavy exposures to radiation and should not be performed on pregnant women.1
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The Naturopathic Approach

Managing Grave’s disease with naturopathic medicine focuses on decreasing the inflammation that triggered, and is contributing to the progression of, your autoimmunity. This involves fundamental changes to food, lifestyle, and stress management, including supplementing the levels of vitamins and minerals that support the regulatory processes in the body, as well as herbal remedies that target the root cause of your condition. 
  • Magnesium. Patients with autoimmune hyperthyroidism often have decreased levels of magnesium in the blood and supplementation may be needed to prevent nutritional deficiency which can cause fatigue, weakness, shortness of breath, palpitations, and insomnia.
  • Potassium. Reduced levels of potassium can be present in patients with autoimmune hyperthyroidism. Since adequate levels of potassium in the blood are important to protect your heart from arrhythmias causing harm and damage, potassium supplementation may be required. However, since too much or too little potassium can cause a dangerous, or even fatal, arrhythmia, it is vital to speak to your healthcare providers before supplementing. 
  • L-Carnitine. L-Carnitine prevents entry of thyroid hormones into the nuclei of the cell, thereby opposing the effects of high thyroid hormone levels. 
  • Vitamin B12. Vitamin B12 is also beneficial in reducing the adverse effects of your antithyroid medications, such as growth depression.

Botanical Medicine

Herbal remedies are effective treatment options that help regulate your thyroid hormone levels, often with fewer and milder side effects than pharmaceutical medications. Additionally, the healing properties of herbal remedies are not limited to relieving a single symptom, as they help the body regain and nurture its natural balance. Herbal remedies for autoimmune hyperthyroidism may include:
  • Lemon Balm (Melissa officinalis)
  • Ashwagandha (Withania somnifera)
  • Motherwort (Leonurus cardiaca)
  • Black Radish (Raphanus sativa var. niger)
  • Rosemary (Rosmarinus officinalis) ​
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Improving Your Thyroid Health

The effects of autoimmune hyperthyroidism in the body can be prevented with prompt diagnosis and holistic strategies that help your body heal naturally and regulate its thyroid hormone levels. Since people with a family history of Grave’s disease may have higher chances of developing the condition, knowing your risk factors and genetic susceptibility are important in avoiding triggers and exacerbations. Interestingly, autoimmune hypothyroidism (Hashimoto’s thyroiditis) and Grave’s disease may occur in the same person! People who are susceptible or have been diagnosed with either disease should be adequately tested and monitored. Your naturopathic doctors are committed to guiding you in exploring the best holistic options and helping you work together with your allopathic healthcare providers to achieve optimal health. Take the first step to wellness today!
 
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Author

Kate Nemenzo's passion for holistic health has led her to become a registered nurse who promotes optimal care throughout her patient’s therapeutic journey. When not writing, she spends her time crocheting, watching Korean dramas, and playing the guitar!

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​This article is for educational purposes only and is not intended as medical advice. Please consult your licensed naturopathic physician or other licensed healthcare provider before making changes to your medications or supplements. Disclosures & Policies: This and other blog posts may contain affiliate links. Please view our disclosures page for more information.

REFERENCES:
  1. Pokhrel B, Bhusal K. Graves Disease. [Updated 2023 Jun 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK448195/
  2. Shahid MA, Ashraf MA, Sharma S. Physiology, Thyroid Hormone. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK500006/
  3. Gaby A. Nutritional Medicine. Fritz Perlberg Publishing; 2017.

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